Laurie Metcalf is an actress probably best known for her performance as Jackie Harris on the ABC sitcom Roseanne and has also had series television roles as Carolyn Bigsby on Desperate Housewives and Mary Cooper on The Big Bang Theory.

Her motion picture roles include the voice of Mrs. Davis in the Toy Story film series and the character Debbie Loomis/Debbie Salt in Scream 2.

Metcalf frequently works in Chicago theater, where she is known for her performance in the 1983 revival of Lanford Wilson's play Balm in Gilead. She has also appeared in commercials for Plan USA, a humanitarian organization which helps children in need around the world.

She is a three-time Emmy Award winner, and has won both a Theatre World Award and two Obie Awards for her work on the stage. She stars in the HBO series Getting On.